David W. Grainger

University Distinguished Professor and Chair, Department of Bioengineering
Distinguished Professor of Pharmaceutics and Pharmaceutical Chemistry 
Adjunct Professor, Department of Orthopedics 
Adjunct Professor, Department of Chemistry
• Excellence in Surface Science Award, Surfaces in Biomaterials Foundation, 2013
• University of Utah Distinguished Graduate and Post Doctoral Scholar Mentor Award, 2010
• Elected Fellow, American Association for the Advancement of Science, 2008
• Clem Alexander von Humboldt Postdoctoral Fellow, University of Mainz, Germany, 1989
Ph.D., Pharmaceutics, University of Utah, 1987
B.A., Engineering modified with Chemistry, Dartmouth College, 1983


Lab: Biomedical Polymers Laboratory

Drug delivery and medical device innovation; bioanalytical sensing, diagnostics and microarrays, foreign body response, device infection and bacterial-surface interactions, drug delivery, antibody drugs, novel vaccines

Current Research:
• Drug delivery systems and novel formulation strategies
• Polymeric biomaterials
• Antimicrobial medical devices, infection and bacterial colonization
• Nucleic acid and protein microarray diagnostics
• Macrophage interactions with biomaterials and the foreign body response
• Novel live vaccine and protein delivery
• Bioanalytical sensing and device miniaturization

New Technical Book Chapters:
1. A. Rao, M.N. Avula, D.W. Grainger, “Aging and the host response to implanted biomaterials,” in Host Response to Biomaterials, S. Badylak, ed., Elsevier, Amsterdam, in press, 2015.

2. M.N. Avula, D.W. Grainger, “Addressing medical device challenges with drug/device combinations,” Chapter 3, in Drug-Device Combinations for Chronic Diseases, R. Siegel., S.P. Lyu, eds., Wiley, New York, in press, 2015.

3. C-Y Lee, L.J. Gamble, G.M. Harbers, P. Gong, D.W. Grainger, D.G. Castner, “Multi-technique characterization of DNA-modified surfaces for biosensing and diagnostic applications” (Chapter 11) in “Surface Analysis and Techniques in Biology”, ed. V. S. Smentkowski, Springer AG, London, (2013), pp. 289-314; DOI 10.1007/978-3-319-01360-2.

4. C.F. Jones, D.G. Castner, D.W. Grainger, “Surface Adsorbate Processing on Nanomaterials in Host Immune and Toxicological Processing”, in Immunological properties of engineered nanomaterials, (M. Dubrovolaskia, ed.), World Scientific Press, Singapore, 2013, DOI 10.1142/9789814390262_0005.

5. B. Brooks, A. Brooks. D.W. Grainger, “Antimicrobial Technologies in Preclinical and Clinical Medical Devices”, in ‪Biomaterials Associated Infection‬: ‪Immunological Aspects and Antimicrobial Strategies‬, T. F. Moriarty, S.A.J. Zaat, H. Busscher, eds., Springer Verlag, New York, 2012, Chapter 13, pp. 307-354; ISBN 978-1-4614-1030-0.‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬

6. F. Liu, D.W. Grainger, “Fluorinated Biomaterials” in Biomaterials Science, 3rd ed., B.D. Ratner, A.S. Hoffman, J. Lemons, F. Schoen, eds., Academic Elsevier, Amsterdam, 2013, pp. 92-103 (Chapter 1.1.2c) ISBN-10: 0123746264, ISBN-13: 978-0123746269.

7. A. Nel, D.W. Grainger, P.J. Alvarez, S. Badesha, V. Castranova, M. Ferrari, H. Godwin, P. Grodzinski, J. Morris, N. Savage, N. Scott, M. Wiesner, “Nanotechnology Environmental, Health, and Safety Issues,” Chapter 4 in: Nanotechnology Research Directions for Societal Needs in 2020: Retrospective and Outlook (M.C. Roco, C.A. Mirkin, M.C. Hersam, eds.) NSF/WTEC report, 2011, Springer, Boston, USA, pp. 610.

8. F. Liu, D.W. Grainger, “Fluorinated Biomaterials” in Comprehensive Biomaterials vol 1, Chapter 128, eds. P. Ducheyne, K. Healy, D.W. Grainger, J. Kirkpatrick, D. Hutmacher, Elsevier, Amsterdam (ISBN 978-0-08-055302-3), 2011, pp 513-525.

9. D.G. Castner, D.W. Grainger, “Surface analytical methods: in situ and UHV techniques” in Comprehensive Biomaterials – vol 3, chapter 301, eds. P. Ducheyne, K. Healy, D.W. Grainger, J. Kirkpatrick, D. Hutmacher, Elsevier, Amsterdam (ISBN 978-0-08-055302-3), 2011, pp 1-22.

10. D. Holt, D.W. Grainger, “Chapter 6: Host-Implant Response”, in An Introduction to Biomaterials, 2nd ed., (J.O. Hollinger, ed), CRC Press, Boca Raton, FL, ISBN-13: 978-1439812563, (2011).

11. G. Harbers, D.W. Grainger, “Chapter 5: Cell-Materials Interactions: Fundamental Design Issues for Tissue Engineering and Clinical Considerations”, in An Introduction to Biomaterials, 2nd ed. (J.O. Hollinger, ed.), CRC Press, Boca Raton, FL, ISBN-13: 978-1439812563, (2011).

12. J. Veranth, H. Ghandehari, D.W. Grainger, “Nanoparticles in the lung”, in Volume 8 Respiratory Toxicology (G.S. Yost, ed.,), Comprehensive Toxicology series, Elsevier, Oxford, UK, (Chapter 8.23) pp. 453-566 (2010). ISBN 978-0-08-046868-6.


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3227 SMBB
University of Utah
Salt Lake City, Utah