Selected Publications


Diekjürgen D, Grainger DW, Polysaccharide matrices used in 3D in vitro cell culture systems. Biomaterials 2017 Jun 21;141:96-115

Abou-El-Enein M, Duda GN, Gruskin EA, Grainger DW, Strategies for Derisking Translational Processes for Biomedical Technologies. Trends Biotechnol 2017 Feb;35(2):100-108

Jones Z, Brooks AE, Ferrell Z, Grainger DW, Sinclair KD, A resorbable antibiotic eluting bone void filler for periprosthetic joint infection prevention. J Biomed Mater Res B Appl Biomater 2016 Nov;104(8):1632-1642

Deans TL, Grainger DW, Fussenegger M, Synthetic Biology: Innovative approaches for pharmaceutics and drug delivery. Adv Drug Deliv Rev 2016 Oct 1;105(Pt A):1-2

Aamodt JM, Grainger DW, Extracellular matrix-based biomaterial scaffolds and the host response. Biomaterials 2016 Apr;86:68-82

Avula M, Jones D, Rao AN, McClain D, McGill LD, Grainger DW, Solzbacher F, Local release of masitinib alters in vivo implantable continuous glucose sensor performance. Biosens Bioelectron 2016 Mar 15;77:149-56

Falconer JL, Christie RJ, Pollard EJ, Olsen SC, Grainger DW, Live RB51 vaccine lyophilized hydrogel formulations with increased shelf life for practical ballistic delivery. Int J Pharm 2016 Feb 10;498(1-2):187-94

Winters AA, Bou-Ghannam S, Thorp H, Hawayek JA, Atkinson DL, Bartlett CE, Silva FJ, Hsu EW, Moreno AP, Grainger DA, Patel AN, Evaluation of Multiple Biological Therapies for Ischemic Cardiac Disease. Cell Transplant 2016;25(9):1591-1607

Grainger DW, Bae YH, The 17th International Symposium on Recent Advances in Drug Delivery, June 14-17, 2015, Salt Lake City, UT, USA. Preface. J Control Release 2015 Dec 28;220(Pt B):569-70

Auer JA, Grainger DW, Fracture management in horses: Where have we been and where are we going? Vet J 2015 Oct;206(1):5-14Hofmann-Amtenbrink M, Grainger DW, Hofmann H, Nanoparticles in medicine: Current challenges facing inorganic nanoparticle toxicity assessments and standardizations. Nanomedicine 2015 Oct;11(7):1689-94

Chamberlain LM, Holt-Casper D, Gonzalez-Juarrero M, Grainger DW, Extended culture of macrophages from different sources and maturation results in a common M2 phenotype. J Biomed Mater Res A 2015 Sep;103(9):2864-74

Grainger DW, Fat Prospects for Healing Cutaneous Wounds: New Activities Under the Sheets. Diabetes 2015 Aug;64(8):2717-9

Gustafson HH, Holt-Casper D, Grainger DW, Ghandehari H, Nanoparticle Uptake: The Phagocyte Problem. Nano Today 2015 Aug;10(4):487-510

Grainger DW, Wound healing: Enzymatically crosslinked scaffolds. Nat Mater 2015 Jul;14(7):662-3

Holt-Casper D, Theisen JM, Moreno AP, Warren M, Silva F, Grainger DW, Bull DA, Patel AN, Novel xeno-free human heart matrix-derived three-dimensional scaffolds. J Transl Med 2015 Jun 18;13:194

Volk HD, Stevens MM, Mooney DJ, Grainger DW, Duda GN, Key elements for nourishing the translational research environment.Sci Transl Med 2015 Apr 8;7(282):282cm2

Brooks BD, Sinclair KD, Grainger DW, Brooks AE, A resorbable antibiotic-eluting polymer composite bone void filler for perioperative infection prevention in a rabbit radial defect model. PLoS One 2015;10(3):e0118696

Duda GN, Grainger DW, Frisk ML, Bruckner-Tuderman L, Carr A, Dirnagl U, Einhäupl KM, Gottschalk S, Gruskin E, Huber C, June CH, Mooney DJ, Rietschel ET, Schütte G, Seeger W, Stevens MM, Urban R, Veldman A, Wess G, Volk HD, Changing the mindset in life sciences toward translation: a consensus. Sci Transl Med 2014 Nov 26;6(264):264cm12

Astashkina AI, Jones CF, Thiagarajan G, Kurtzeborn K, Ghandehari H, Brooks BD, Grainger DW, Nanoparticle toxicity assessment using an in vitro 3-D kidney organoid culture model. Biomaterials 2014 Aug;35(24):6323-31

Brooks BD, Sinclair KD, Davidoff SN, Lawson S, Williams AG, Coats B, Grainger DW, Brooks AE, Molded polymer-coated composite bone void filler improves tobramycin controlled release kinetics. J Biomed Mater Res B Appl Biomater 2014 Jul;102(5):1074-83

Smock KJ, Schmidt RL, Hadlock G, Stoddard G, Grainger DW, Munger MA, Assessment of orally dosed commercial silver nanoparticles on human ex vivo platelet aggregation. Nanotoxicology 2014 May;8(3):328-33

Avula MN, Rao AN, McGill LD, Grainger DW, Solzbacher F, Foreign body response to subcutaneous biomaterial implants in a mast cell-deficient Kit(w-Sh) murine model. Acta Biomater 2014 May;10(5):1856-63


Grainger DW, Cell-based drug testing; this world is not flat. Adv Drug Deliv Rev 2014 Apr;69-70:vii-xiAstashkina A, Grainger DW, Critical analysis of 3-D organoid in vitro cell culture models for high-throughput drug candidate toxicity assessments. Adv Drug Deliv Rev 2014 Apr;69-70:1-18

Silva FJ, Holt DJ, Vargas V, Yockman J, Boudina S, Atkinson D, Grainger DW, Revelo MP, Sherman W, Bull DA, Patel AN,Metabolically active human brown adipose tissue derived stem cells. Stem Cells 2014 Feb;32(2):572-81

Degooyer J, Davidoff SN, Brooks BD, Grainger DW, Brooks AE, Polymer-controlled extended combination release of silver and chlorhexidine from a bone void filler. Biomed Sci Instrum 2014;50:47-53

Wang Y, Liu J, Zhang J, Wang L, Chan J, Wang H, Jin Y, Yu L, Grainger DW, Ying W, A cell-based pharmacokinetics assay for evaluating tubulin-binding drugs. Int J Med Sci 2014;11(5):479-87

Munger MA, Radwanski P, Hadlock GC, Stoddard G, Shaaban A, Falconer J, Grainger DW, Deering-Rice CE, In vivo human time-exposure study of orally dosed commercial silver nanoparticles. Nanomedicine 2014 Jan;10(1):1-9

Moriarty TF, Grainger DW, Richards RG, Challenges in linking preclinical anti-microbial research strategies with clinical outcomes for device-associated infections. Eur Cell Mater 2014 Sep 12;28:112-28; discussion 128

Avula MN, Rao AN, McGill LD, Grainger DW, Solzbacher F, Modulation of the foreign body response to implanted sensor models through device-based delivery of the tyrosine kinase inhibitor, masitinib. Biomaterials 2013 Dec;34(38):9737-46

Grainger DW, van der Mei HC, Jutte PC, van den Dungen JJ, Schultz MJ, van der Laan BF, Zaat SA, Busscher HJ, Critical factors in the translation of improved antimicrobial strategies for medical implants and devices. Biomaterials 2013 Dec;34(37):9237-43

Brooks AE, Brooks BD, Davidoff SN, Hogrebe PC, Fisher MA, Grainger DW, Polymer-controlled release of tobramycin from bone graft void filler. Drug Deliv Transl Res 2013 Dec;3(6):518-30

Wang Y, Grainger DW, Developing siRNA therapies to address osteoporosis. Ther Deliv 2013 Oct;4(10):1239-46

Grainger DW, Connecting drug delivery reality to smart materials design. Int J Pharm 2013 Sep 15;454(1):521-4

Grainger DW, All charged up about implanted biomaterials. Nat Biotechnol 2013 Jun;31(6):507-9

Davidoff SN, Lawson ST, Grainger DW, Brooks AE, Scanning electron image analysis to monitor of implant degradation and host healing following implantation of a drug-eluting bone graft void filler - biomed 2013. Biomed Sci Instrum 2013;49:165-71

Richards RG, Moriarty TF, Miclau T, McClellan RT, Grainger DW, Advances in biomaterials and surface technologies. J Orthop Trauma 2012 Dec;26(12):703-7